Engage and coordinate actors representing all relevant stakeholder groups to form a strong multi-year consortium representing the Swedish health data ecosystem (healthcare, academia, industry, patient groups, and public organizations). Identify actors who want to implement OMOP and OHDSI tools.

Deliverables:

• 1.1 Established multi-helix consortium with stakeholders supporting a multi-year transformation initiative for increased OMOP/OHDSI use in Sweden
• 1.2 Mature dialogue and clear timeline for forming the national Swedish OMOP node with researchers, data partners and other actors
• 1.3 List of actors interested in implementing OMOP/OHDSI in Sweden
• 1.4 Map of local actors with capacity to support OMOP implementation efforts in Sweden
• 1.5 Project results officially handed over to SFMI and other potential recipients identified during the project
• 1.6 Project delivered on time, within scope, with regular contact with SweLife to meet expectations and requirements, plus status and financial reporting to funders
• 1.7 Communication: Key insights and results communicated through participants' and industry organizations' communication channels (e.g., social media) and through events

Define OMOP's target groups, their respective problem formulations, use cases, and needs. Clarify how OMOP and OHDSI can contribute to the Swedish health data ecosystem and document the value proposition for different stakeholders.

Deliverables:

• 2.1 Documented descriptions of target groups, use cases, challenges, needs, benefits and expected results from using OMOP and OHDSI
• 2.2 Documentation clarifying how OMOP/OHDSI can address problems and challenges formulated in the national life science strategy

Gather experiences, recommendations, success stories, and best practices from leading OMOP/OHDSI countries and experts. Collect input from international/national expertise and early users in Sweden, and adapt this to relevant national and European investigations, initiatives, established entities, and regulatory frameworks.

Deliverables:

• 3.1 Documented experiences and recommendations based on OMOP/OHDSI experts and practitioners from various parts of the world
• 3.2 List of relevant international standards, best practices, project examples and solutions for secondary use of health data
• 3.3 List of relevant national investigations, initiatives, established organizations, functions and regulatory frameworks (and possibly European ones if needed)
• 3.4 Documented connections and relationships between OMOP/OHDSI and selective investigations, initiatives, organizations and supervisory bodies related to secondary use of health data
• 3.5 International advisory group with leading experts supporting Sweden's OMOP work

This work package will perform a pre-study on how Uppsala Clinical Research Center's (UCR) registry platform and its organization can integrate and utilize OMOP in the best way. The study aims to identify use cases and opportunities where OMOP can create added value for UCR's operations, studies and strategic collaborations. Alternative ways to implement OMOP in UCR's operations and registry platform will be identified and defined. Furthermore, UCR's source data will be analyzed regarding structure, quality, terminologies, technology and standards to estimate transformation efforts.

Deliverables:

A final report, including a summary of analysis, results, alternatives and recommendations:

• 4.1 Strategic and organizational analysis
• 4.2 Data and technology analysis
• 4.3 Alternative and recommended approaches for implementing OMOP
• 4.4 Draft roadmap with estimated timelines
• 4.5 Internal and external resource needs
• 4.6 Requirements and specifications (technical, personnel, ownership, processes)
• 4.7 Training needs
• 4.8 Cost estimates

Implementation of OMOP and OHDSI tools to enable fast, efficient and safe studies in the field of respiratory diseases, based on observational harmonized registry and administrative health data from selected authorities (National Board of Health and Welfare, Social Insurance Agency), regions (VGR, Region Stockholm, Region Skåne) and the Swedish Intensive Care Registry (SIR).

Deliverables:

Results from the data harmonization:

• 5.1 Initial analysis report
• 5.2 Document with the mapping of the data structure including validation
• 5.3 Results from the semantic mapping including validation

Results from the implementation of technical data infrastructure and software (OHDSI):

• 5.4 Document with infrastructure design
• 5.5 Documentation for the implementation
• 5.6 Docker containers (ETL, OHDSI tools, custom tools/scripts)
• 5.7 ETL source code (transfer of GitHub repository)
• 5.8 Report with the data validation
• 5.9 Documentation of maintenance guidelines
• 5.10 Training and educational materials

Results from studies and dissemination of the project's results and lessons learned:

• 5.11 Summary documentation from completed studies
• 5.12 Completed dissemination of results and lessons learned to project participants and Swedish target groups (session + communication)

Continued activation, mobilization and further development of OMOP 4 Sweden, for increased understanding, engagement and accelerated use of the international data model OMOP for harmonization and effective reuse of Swedish health data.

Deliverables:

• 6.1 A doubling of the number of engaged players in OMOP 4 Sweden (16 → 32)
• 6.2 Evidence of increased interest and, above all, practical activity within the consortium (i.e. projects)
• 6.3 ≥6 workshops, seminars and events arranged to drive understanding and engagement
• 6.4 ≥3 of target group 1 actors showing activity with OMOP (the National Board of Health and Welfare is priority #1)
• 6.5, 6.6, 6.8 Establish the national node of OHDSI Sweden under the leadership of 1-2 established academic/healthcare institutions together with OMOP 4 Sweden
• 6.7 Alignment with other health informatics standardization bodies and institutions (e.g. SFMI/openEHR, HL7 FHIR, ...)
• 6.9 ≥5 players interested in implementing and/or using OMOP
• 6.10 An established active pipeline of projects implementing OMOP in Sweden, harmonizing its health data and making it available for reuse
• 6.11 Ongoing dialogues with strategic players, decision-makers, relevant national initiatives on harmonization of Swedish health data and use of OMOP
• 6.12 Increased engagement from national actors in how Sweden could utilize and integrate OMOP for increased harmonization and reuse of Swedish health data
• 6.13 Increased financial support, public and private, for mobilization, increased understanding, implementation and use of OMOP